The resting membrane potential of nerve and muscle typically is?

The resting membrane potential of nerve and muscle cells is typically in the range of -70 to -90 mV. This potential is primarily the result of the distribution of ions across the cell membrane, mainly influenced by the permeability of the membrane to potassium ions (K+) and the activity of the sodium-potassium pump, which helps maintain this ionic gradient.

A value in this range indicates that the inside of the cell is negatively charged compared to the outside, creating an electrochemical gradient that is essential for various cellular functions, including the generation of action potentials in nerves and muscle contraction. This negative resting potential is crucial for the excitability of these cells, as it allows them to respond to stimuli effectively and propagate electrical signals.

A potential that is too positive or less negative would mean a failure in maintaining the necessary conditions for nerve impulses and muscle contractions, highlighting the importance of staying within the -70 to -90 mV range for normal function.