Which nerve conduction parameter is often used to evaluate demyelinating neuropathies?

Conduction velocity is a critical parameter used to evaluate demyelinating neuropathies because it measures the speed at which an electrical impulse travels along a nerve. In demyelinating conditions, the myelin sheath is damaged or destroyed, which leads to slower conduction velocities. By assessing conduction velocity, clinicians can identify the extent of myelin impairment, differentiate between various types of neuropathies, and formulate appropriate treatment plans.

Conduction latency and amplitude are also important in nerve conduction studies, but they serve different functions. Latency measures the time taken for the impulse to travel and can indicate delays in conduction that occur with demyelination, while amplitude indicates the strength of the nerve signal, which may not specifically relate to myelin integrity. Resting potential is a baseline measurement of nerve cell excitability and does not directly assess the conduction characteristics that are altered in demyelinating neuropathies. Thus, conduction velocity is the most relevant parameter for evaluating these conditions.